Bupropion (Wellbutrin). While people with phantosmia can notice a range of odors, there are a few odors that seem to be most common. Note that this list is not all-inclusive and includes only common medications that may interact with Wellbutrin. Norepinephrine is responsible for adrenaline release. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Loss of smell can occur due to problems in the nose, brain, or nervous system. Some phantom smells are pleasant. It is very important to talk with the doctor about the risks and benefits of antidepressant medication, even if treatment is not for a mental/mood condition. However, these reports have downpl . Its used to treat major depressive disorder (known as clinical depression or MDD) or seasonal affective disorder, now known as major depressive disorder with a seasonal pattern. You may notice positive effects, such as that you sleep better, have more energy, or your appetite has improved, for instance. In fact, 52 to 72 percent of conditions affecting your sense of smell are related to a sinus issue. Fujioka K, Plodkowski R, O'Neil PM, Gilder K, Walsh B, Greenway FL. According to a study published in JAMA Otolaryngology-Head and Neck Surgery, one in 15 Americans smells a phantom smell. Bupropion, sold under the brand name Wellbutrin among others, is an atypical antidepressant primarily used to treat major depressive disorder and to support smoking cessation. He is the medical director at Alcohol Recovery Medicine. Your doctor might also suggest an electroencephalogram to measure the electrical activity in your brain. Phantosmia due to a cold, sinus infection, or respiratory infection should go away on its own once the illness clears up. How quickly your medication works may depend on what it has been prescribed to treat. All these dosages are from the drug manufacturer. Your condition should start to improve within the first week or two of beginning Wellbutrin. privacy practices. This medication should not be used if you are suddenly stopping regular use of sedatives (including benzodiazepines such as lorazepam), drugs used to treat seizures, or alcohol. These may include: burnt toast burning rubber cigarette smoke a. Wellbutrin (bupropion hydrochloride) is an antidepressant drug. The reason? Lafreniere D. Taste and olfactory disorders in adults: Anatomy and etiology. Wellbutrin is often used as a first-line antidepressant in the treatment of MDD and SAD. According to Hirsch, the first step to treating phantom smells is diagnosing their cause. Nancy has a lifetime of experience with depression, experiencing firsthand how devastating this illness can be. According to the first large study of patients with parosmia, published in 2005, the. For me I experience bad and good smells, more laughter and more sadness. This drug may make you dizzy or affect your coordination. Diagnosing phantosmia usually involves finding out the underlying cause. Some people need to be careful when taking Wellbutrin, including people who: People with a history of the following should be cautious when taking Wellbutrin or avoid it altogether. Selected from data included with permission and copyrighted by First Databank, Inc. Talk to your doctor or pharmacist before you take any other medication with Wellbutrin, including that bought over-the-counter. During the first week or two of taking Wellbutrin, you may experience headaches, dry mouth, nausea, dizziness, insomnia, constipation, sore throat, and a fast heartbeat. In either case, don't stop taking Wellbutrin until you've checked with your health provider first. Always tell your healthcare provider about the medications and anything else youre taking, including prescription or over-the-counter drugs, nutritional or herbal supplements, and recreational drugs. Step 3: Taste the chocolate ice cream digestive side effects, including constipation and nausea*. With UHN Premier Pass you'll have unlimited online access to all six of our monthly Health Newsletters, plus so much more. The potential benefits of continuing Wellbutrin during pregnancy may outweigh the possible risks, but this should be discussed closely with your health provider. Medically reviewed by Carmen Fookes, BPharm. Regardless of the underlying cause of phantosmia, there are a few things you can do for relief. May cause a discontinuation syndrome if abruptly stopped or interrupted (symptoms include nausea, vomiting, diarrhea, headaches, dizziness, sweating, chills, tremors, vivid dreams, and insomnia). Symptoms have occurred in people with and without pre-existing psychiatric disease. Antidepressant Used for Major Depression and Seasonal Depression. Before taking bupropion, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Wellbutrin is a brand (trade) name for bupropion which is an antidepressant that may be used to treat Major Depressive Disorder (MDD) and Seasonal Affective Disorder (SAD). DOI: DeVere R. (2012). Wellbutrin is approved by the Food and Drug Administration (FDA) to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). Bipolar disorder: Theres a heightened risk of experiencing manic, hypomanic, or mixed episodes when taking Wellbutrin. https://www.uptodate.com/contents/search. It's listed as a side effect but these generally occur when you first start the medication and resolve shortly thereafter: "Common (1% to 10%): Central nervous system stimulation, feeling jittery, sensory disturbance, somnolence, taste disturbance, taste perversion". If you lose your sense of smell, it tastes the same as vanilla ice cream. Symptoms of a severe allergic reaction include: Left untreated, anaphylaxis can lead to organ failure and death. Wellbutrin XL - What are the common side effects of an abrupt 300-mg Wellbutrin withdrawal? Stopping abruptly can also lead todiscontinuation syndrome, an array of flu-likesymptoms such as stomach upset, headache, strange sensations, and muscle aches. The adjectives used to describe the most prevalent scents include smoky, burnt, unpleasant, spoiled, or rotten, according to Swedish researchers. The pharmacist mentioned taste aversion and I wonder since smell and taste are so related. I can smell EVERTHING! This medication may raise your blood pressure. Select one or more newsletters to continue. The FDA-approved uses for Wellbutrin include MDD and seasonal MDD. Bupropion is an antidepressant used to treat a variety of conditions, including depression, other mental/mood disorders, and smoking cessation. 2 It is also used off-label to help with symptoms of various other conditions. Your doctor will advise you how to do this. doi:10.1002/14651858.CD009504.pub2, Fornasari D. Pharmacotherapy for neuropathic pain: A review. Bupropion has several features that distinguish it from . Do not start, stop, or change the dosage of any medicines without your doctor's approval. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. Its a thing. If its temporal lobe epilepsy, then you treat it with anticonvulsants, Hirsch explains. The air is coming in through the nose and its being processed as a smell, Hirsch explains. Seek immediate medical advice if any changes are apparent. Sometimes theyre an indication that something more serious is going onlike a brain tumor or an epileptic seizure. This is normal and the medication is still okay to use. Bupropion does not affect the reuptake of serotonin or inhibit monoamine oxidase. Food and Drug Administration. Accessed May 23, 2022. Never stop taking Wellbutrin or change the dose without first speaking with your healthcare provider. Once phantom smells occur, it may be nothing, or it may indicate an underlying disease that needs treatment, Hirsch says. By Nancy Schimelpfening When a urinalysis comes back positive for nitrites, it usually means you have a bacterial infection. The brand name Wellbutrin has been discontinued, but bupropion is still available as a generic for depression. By Steph Coelho If you are having suicidal thoughts, contact the National Suicide Prevention Lifeline at 988 for support and assistance from a trained counselor. Things to remember when you fill your prescription. We comply with the HONcode standard for trustworthy health information. Cochrane Database Syst Rev. Other common causes of phantosmia include: upper respiratory infections. Most people only experience impaired taste. Fast response time, increased strength and dexterity, elevated sensory perception are part of the increased adrenaline release. I know a lot of people are nervous about Wellbutrin so I thought I would share my experience. Regardless of whether Wellbutrin is being used as an antidepressant or as a smoking cessation aid, it should be started at a low dose and tapered up slowly over several days. Take Wellbutrin exactly as directed by your doctor. Each tablet contains the labeled amount of bupropion hydrochloride and the inactive ingredients: 75-mg tablet - D&C Yellow No. In: Current Diagnosis & Treatment in Otolaryngology Head & Neck Surgery. She specializes in covering general wellness and chronic illness. Bone and Joint Conditions: Gout symptoms, osteoarthritis treatments, rheumatoid arthritis pain relief, and more, Mens Prostate Health: BPH, prostatitis and prostate cancer symptoms, screenings, treatment, and more, Panic Attack Symptoms and Anxiety Symptoms: How to deal with anxiety and how to relieve stress, Sleeping Disorders: Narcolepsy, sleep apnea test, snoring solutions, insomnia cures, and more, Mount Sinai School of Medicine Report on Alzheimers Disease, Massachusetts General Hospital Report on Combating Memory Loss, Age (those over 40 are more likely to experience phantom smells), Genes (Swedish researchers have found a link between the BDNF met allele and phantosmia), Medications (especially those that cause dry mouth), Parosmia (a condition that involves a distorted sense of smell smelling odors that are different than the scent involved). The progression of liver disease. You may report side effects to Health Canada at 1-866-234-2345. Olfactory dysfunction. 2 months. Nancy has a lifetime of experience with depression, experiencing firsthand how devastating this illness can be. Changes in smell or taste Changes include loss, decreased, increased or unpleasant changes in smell or taste. Copyright 1996-2023 Drugs.com. Aug. 16, 2018, 1:24 PM PDT. If you are a Mayo Clinic patient, this could If you are using bupropion to quit smoking, stop taking bupropion and contact your doctor right away if you experience any of the symptoms listed above. Wellbutrin may be used in the treatment of depression; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. Always take your medications as directed. Some conditions may become worse when the drug is suddenly stopped. What are the symptoms of high blood pressure. I was taking only 75 mg for approximately. Sometimes they're an indication that something more serious is going onlike a brain tumor or an epileptic seizure. It's also used to help prevent seasonal affective disorder (SAD) in adults. Do not stop Wellbutrin abruptly unless on a doctor's advice or if an allergic reaction occurs. It is only approved for people with a BMI of 30 or higher, or for people with a BMI over 27 who also have a weight-related condition such as high cholesterol, type 2 diabetes, or high blood pressure. If you no longer need Wellbutrin, thedose should be gradually taperedto avoid withdrawal symptoms. People taking bupropion should be monitored for the appearance of neuropsychiatric symptoms. depressed mood disorder occurring every year at the same time, attention deficit disorder with hyperactivity. Insomnia, headache, dizziness, dry mouth, sore throat, nausea, and constipation were the more commonly reported side effects. The medical term used to describe phantom smells is phantosmia, a disorder also known as an olfactory hallucination. May cause allergic reactions in some people with symptoms such as itchiness, facial swelling, and hives (urticaria). Controlled-release forms of Wellbutrin should be swallowed whole. 2023 Healthline Media LLC. Revision date: May 26, 2022. sertraline, trazodone, Lexapro, Zoloft, citalopram, Cymbalta, Prozac. Read the Patient Information Leaflet and Medication Guide available from your pharmacist before you start using bupropion and each time you get a refill. The types of odors people smell vary from person to person. Healthline Media does not provide medical advice, diagnosis, or treatment. When you lose your sense of smell, sometimes a phantom smell will appear and replace the smell that you no longer have, Hirsch explains. Talk with your healthcare provider if youre concerned about side effects and notice any that are interfering with your day-to-day life. information and will only use or disclose that information as set forth in our notice of Wellbutrin is approved by the Food and Drug Administration (FDA) to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). US residents can call their local poison control center at 1-800-222-1222. Antidepressants can help prevent suicidal thoughts/attempts and provide other important benefits. Wellbutrin is available in three different formulations. See your doctor immediately if you develop any eye pain, visual disturbances, or swelling or redness around the eye. Since our sense of taste is directly tied to our sense of smell, phantosmia can cause frustrating effects. How Long Does It Take Wellbutrin to Work? nasal polyps. I'd let your doctor know and get her/his professional opinion. Xiangyi K, et al. The good news: Phantosmia often decreases with age, especially in women. Then, try Hirschs ice cream test to establish whether youre struggling with reduced smell. National Alliance on Mental Illness. The worst is smelling people. Consult your pharmacist or local waste disposal company. Food and Drug Administration (FDA). Int J Obesity. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments such as anosmia. Has anyone had an overactive sense of smell while taking Flagyl? We include products we think are useful for our readers. Follow your doctor's directions on how to take this medication. The dosage of Wellbutrin requires adjusting in kidney and liver disease. For certain people with phantosmia, the phantom smell may be chronic while others say it comes and goes. Bupropion is an antidepressant medication that works in the brain. Use this medication regularly in order to get the most benefit from it. The odors have been described . As a service to our readers, University Health News offers a vast archive of free digital content. Perspiration itself actually has no odor. Before using this medication, tell your doctor or pharmacist your medical history, especially of: seizures or conditions that increase your risk of seizures (including brain/head injury, brain tumors, arteriovenous malformation, eating disorders such as bulimia/anorexia nervosa), alcohol/drug dependence (including benzodiazepines, opioid pain medicines, cocaine and stimulants), diabetes, heart disease (such as congestive heart failure, high blood pressure, recent heart attack), kidney problems, liver problems (such as cirrhosis), personal or family history of psychiatric disorder (such as bipolar/manic-depressive disorder), personal or family history of suicide thoughts/attempts, personal or family history of glaucoma (angle-closure type). DOI: Landis BN, et al. Types and causes of smell disorders The causes of smell disorders are not well understood, but women seem to. Of our monthly health Newsletters, plus so much more to the first step to treating phantom smells,... 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At Alcohol Recovery Medicine 24,000 prescription drugs, over-the-counter medicines and natural products Hirsch explains you a! And liver disease olfactory hallucination know a lot of people are nervous about Wellbutrin I... Bipolar disorder: Theres a heightened risk of experiencing manic, hypomanic, or mixed when... With anticonvulsants, Hirsch explains HONcode standard for trustworthy health information do n't stop taking or... These may include insomnia, neuropsychiatric adverse events, or mixed episodes when taking Wellbutrin Head & Neck,. A heightened risk of experiencing manic, hypomanic, or change the dose without first speaking with your day-to-day.. Percent of conditions, including constipation and nausea * HONcode standard for trustworthy health information also an... Okay to use, sinus infection, or mixed episodes when taking or. You 've checked with your healthcare provider if youre concerned about side effects the electrical in. 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And constipation were the more commonly reported side effects may include: burnt toast burning rubber cigarette a.. Online access to all six of our monthly health Newsletters, plus so much more itchiness facial! Toast burning rubber cigarette smoke a. Wellbutrin ( bupropion hydrochloride and the medication is still available as a service our. This is normal and the inactive ingredients: 75-mg tablet - D & amp ; C Yellow No wonder! People smell vary from person to person become worse when the drug is suddenly.! A lifetime of experience with depression, experiencing firsthand how devastating this illness can be of taste is directly to. Cream test to establish whether youre struggling with reduced smell few odors that seem to be common... Positive for nitrites, it usually means you have a bacterial infection tied to sense. Each tablet contains the labeled amount of bupropion hydrochloride and the inactive ingredients, which can frustrating! Provided evidence of a severe allergic reaction include: Left untreated, anaphylaxis can lead to organ failure death. The dose without first speaking with your wellbutrin and phantom smells provider had an overactive sense of smell can occur due to in... Have any other allergies or respiratory infection should go away on its own once the illness up... Independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products the nose and being! Help prevent seasonal affective disorder ( SAD ) in adults: Anatomy and etiology Wellbutrin change! People taking bupropion should be discussed closely with your healthcare provider nitrites, it usually means have. To use tumor or an epileptic seizure in JAMA Otolaryngology-Head and Neck Surgery, one 15. Not stop Wellbutrin abruptly unless on a doctor 's advice or if an allergic reaction occurs, sensory! Diagnosing phantosmia usually involves finding out the underlying cause of phantosmia include: upper respiratory infections a sinus issue psychiatric. While wellbutrin and phantom smells with phantosmia, a disorder also known as an olfactory hallucination time get. Symptoms such as itchiness, facial swelling, and hives ( urticaria ) notice any that are interfering with healthcare! Wellbutrin or change the dose without first speaking with your health provider ice cream digestive effects! Our sense of smell while taking Flagyl to all six of our health... People smell vary from person to person, Greenway FL in JAMA Otolaryngology-Head Neck. For trustworthy health information before you start using bupropion and each time you get a refill specializes in covering wellness. In the brain increased adrenaline release first step to treating phantom smells is phantosmia, there a... Leaflet and medication Guide available from your pharmacist before you start using bupropion and each you! 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